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Monotherapy
with Carbon Ion Radiation for Localized
Prostate Cancer
RRecently
the incidence of prostate cancer has been
increasing in Japan, and more than half of
the patients are organ-confined or in
locally advanced stages. For these
patients, radiation therapy is one of the
curative strategy, and many radiological
techniques are being used. Carbon ion
radiation may be a powerful means of
radiotherapy for prostate cancer, because
it shows a Bragg peak in the human body
and gives a high dose of radiation energy
to the prostate without adverse effects to
the surrounding tissues. The Heavy Ion
Medical Accelerator in Chiba (HIMAC) was
built at the National Institute of
Radiological Sciences, and treatment was
initiated with carbon ion radiation for
many kinds of solid tumors (1,2).
Treatment for prostate cancer by HIMAC
started in 1995 and 400 patients have been
treated to date. The patients were divided
into either low-risk group [T1b,c and
T2ab, Gleason score 6, and PSA
(prostate-specific antigen) 20 ng/ml]
or high-risk
group.... See
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