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ERBB2
in Pediatric Cancer: Innocent Until Proven
Guilty
Adult oncologists and their research colleagues
have "led the charge" in the war on cancer. Their
efforts have generated effective new chemotherapies
that target cancer causing molecular alterations.
It is hoped that these successes will be repeated
within the pediatric oncology community. Testing
whether molecular targeted therapies of adult
cancers are also effective against childhood
cancers might allow the rapid introduction of these
exciting new agents into the pediatric clinic.
However, it is imperative that we do not introduce
blindly these agents into the pediatric population.
We must ensure that molecular targets in adult
cancers also fulfill a number of important criteria
within the pediatric
disease.... See
Full Article
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