|
Neoplasms
of the Spinal Cord and Filum Terminale:
Radiologic-Pathologic
Correlation
Intramedullary
spinal cord neoplasms are rare, accounting for
about 4%10% of all central nervous system tumors.
Despite their rarity, these lesions are important
to the radiologist because magnetic resonance (MR)
imaging is the preoperative study of choice to
narrow the differential diagnosis and guide
surgical resection. On contrast materialenhanced MR
images, intramedullary spinal tumors almost always
manifest as expansion of the spinal cord and show
enhancement. Syringohydromyelia and cystic lesions
are frequently associated with intramedullary
tumors. Nontumoral cysts tend to be located at the
poles of the tumors...
See
Full Article
|
Targeting
Human Glioblastoma Cells: Comparison of Nine
Viruses with Oncolytic
Potential
Brain
tumors classified as glioblastomas have proven
refractory to treatment and generally result in
death within a year of diagnosis. We used seven in
vitro tests and one in vivo trial to compare the
efficacy of nine different viruses for targeting
human glioblastoma. Green fluorescent protein
(GFP)-expressing vesicular stomatitis (VSV),
Sindbis virus, pseudorabies virus (PRV),
adeno-associated virus (AAV), and minute virus of
mice i-strain (MVMi) and MVMp all infected
glioblastoma cells. Mouse and human
cytomegalovirus, and simian virus 40 showed only
low levels of infection or GFP expression. VSV and
Sindbis virus ...
See
Full Article
|